The 2010 MTV Movie Awards was the 19th annual ceremony which took place on June 6, 2010 in Los Angeles, California. Aziz Ansari served as a host for the 19th annual ceremony. Voting the nominees began from a list of eligible contestants on March 29, 2010, and ended on April 9, 2010. The nominees itself were announced on May 12, 2010, and the winners were voted by the public.
- Christina Aguilera — Medley: "Bionic/Not Myself Tonight/Woohoo"
- Christopher Mintz-Plasse and Ed Helms — introduced Christina Aguilera.